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ActivityThese two hands-on activities are based on a Howard Hughes Medical Institute 2013 Holiday Lectures on Science video featuring researcher Dr. Charles L. Sawyers. Also available in Spanish.
Animation(32 sec) A useful technique for narrowing down the location of a gene involves comparing the chromosomes of affected siblings. Two sisters with Rett syndrome allow researchers an opportunity to map the most likely location of the gene by excluding areas of the chromosome that are not alike.
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