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  • Genetics of Human Origins and Adaptation

    Genetics of Human Origins and Adaptation

    Lecture

    (58 min 31 sec) Genetic evidence shows that humans evolved in Africa and continue to evolve.

  • Bones, Stones, and Genes: The Origin of Modern Humans

    Bones, Stones, and Genes: The Origin of Modern Humans

    Lecture

    Where and when did humans arise? What distinguishes us from other species? Did our distant ancestors look and behave like us?

  • From Butterflies to Humans

    From Butterflies to Humans

    Lecture

    (58 min 30 sec) How and why butterflies and fruit flies got their spots, and the fossil record for human evolution.

  • Fossils, Genes, and Embryos

    Fossils, Genes, and Embryos

    Lecture

    (58 min 30 sec) The genetic mechanisms by which evolution occurs, and an overview of the evidence for evolutionary theory.

  • Selection in Action

    Selection in Action

    Lecture

    (58 min 29 sec) Comparing the artificial selection of dogs and corn with the natural selection of the stickleback fish.

  • Evolution: Constant Change and Common Threads

    Evolution: Constant Change and Common Threads

    Lecture

    How has the amazing diversity of plants and animals evolved? What can fossils, butterflies, and stickleback fish tell us about the deep common ancestry of all living forms?

  • Balancing the Fat Equation

    Balancing the Fat Equation

    Lecture

    (58 min 20 sec) Dr. Evans reviews how PPARs regulate body weight by controlling whether fat is burned or stored.

  • The Strength of Families: Solving Rett Syndrome

    The Strength of Families: Solving Rett Syndrome

    Lecture

    (58 min 32 sec) Girls with Rett syndrome develop normally for about 18 months and then begin to regress. With the help of affected girls and their families, Dr. Zoghbi and her collaborators searched for the gene responsible for this neurological disorder.

  • Sex and Death: Too Much of a Good Thing

    Sex and Death: Too Much of a Good Thing

    Lecture

    (59 min 6 sec) Having too many chromosomes can lead to too much gene expression. Dr. Meyer explains how the gene that controls dosage compensation in C. elegans works.

  • Hermaphrodites: The Safer Sex

    Hermaphrodites: The Safer Sex

    Lecture

    (56 min 32 sec) Dr. Barbara Meyer explains the value of studying model organisms and introduces the nematode C. elegans.

  • The Meaning of Sex: Genes and Gender

    The Meaning of Sex: Genes and Gender

    Lecture

    Four talks focus on sex determination—the molecular and genetic mechanisms that determine whether an organism will be male, female or a hermaphrodite.

  • Regulation of Sex Determination in C. elegans

    Regulation of Sex Determination in C. elegans

    Clip

    (6 min 4 sec) A demonstration by Dr. Meyer showing how a balance of molecular elements trigger genetic pathways that determine the sex of a C. elegans worm.

  • Clockwork Genes: Discoveries in Biological Time

    Clockwork Genes: Discoveries in Biological Time

    Lecture

    Four lectures highlight the research of two scientists who have made groundbreaking discoveries elucidating the molecular basis of circadian clocks—the internal timekeepers that govern fluctuations in behavior and physiology on a 24-hour cycle.

  • Interview with Dr. Ron Konopka

    Interview with Dr. Ron Konopka

    Interview

    (44 sec) Dr. Benzer is joined by Dr. Ron Konopka for a brief discussion of how the per gene is involved in mammalian clocks.

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