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  • Virus Hunters: Epidemiology of Nipah Virus

    Virus Hunters: Epidemiology of Nipah Virus

    Activity

    In this activity, students will be exploring cases of Nipah virus (NiV) infection as an epidemiologist would, by collecting evidence and making calculations and predictions, based on scientific data.

  • Viral DNA Integration

    Viral DNA Integration

    Activity

    In this hands-on activity, students model how a double-stranded DNA copy of the HIV genome is integrated into the host cell DNA.

  • HIV Reverse Transcription and AZT

    HIV Reverse Transcription and AZT

    Activity

    Students model how the anti-HIV drug AZT (azidothymidine) interferes with the process of viral replication.

  • Think Like a Scientist: Natural Selection in an Outbreak

    Think Like a Scientist: Natural Selection in an Outbreak

    Scientists at Work

    (7 min 29 sec) This video brings us to the front lines of the 2013–2015 Ebola outbreak in west Africa and explains how scientists monitored the evolution of the virus by analyzing its genome.

  • Genetically Modified Mosquitoes

    Genetically Modified Mosquitoes

    Scientists at Work

    (8 min 35 sec) Learn the process by which a line of genetically modified mosquitoes was engineered to reduce populations of Aedes aegypti mosquitoes in the wild.

  • Patterns of Zoonotic Disease

    Patterns of Zoonotic Disease

    Data Point

    In this study, scientists analyzed previously published data on terrestrial mammal zoonotic host species and the pathogens they carry to search for global patterns of zoonotic disease distribution.

  • Virus Hunter: Monitoring Nipah Virus in Bat Populations

    Virus Hunter: Monitoring Nipah Virus in Bat Populations

    Scientists at Work

    (9 min 1 sec) In this video we follow scientists working in Bangladesh as they test fruit bat populations to determine whether they are infected with Nipah virus—a potentially deadly virus when passed on to humans.

  • Dengue Virus Enters a Cell

    Dengue Virus Enters a Cell

    Animation

    (1 min 33 sec) Infection begins when the dengue virus uses receptors on an immune cell's surface to gain entry and release its genome.

  • Dengue Virus Life Cycle

    Dengue Virus Life Cycle

    Animation

    (4 min 12 sec) Dengue virus has sophisticated mechanisms for entering a cell, for replicating its RNA genome, and for translating proteins.

  • HIV life cycle

    HIV life cycle

    Animation

    (4 min 52 sec) How HIV infects a cell and replicates itself using reverse transcriptase and the host's cellular machinery.

  • AZT blocks reverse transcriptase

    AZT blocks reverse transcriptase

    Animation

    (1 min 46 sec) HIV's reverse transcriptase mistakes AZT for thymidine. Once incorporated, AZT stops reverse transcription.

  • U.S. AIDS epidemic

    U.S. AIDS epidemic

    Animation

    A visual representation of the U.S. AIDS epidemic from 1981 to 1997. Each dot represents 30 cases.

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