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Showing 1-10 of 10 Resources
  • Viral Lysis and Budding

    Viral Lysis and Budding

    Activity

    This activity outlines two demonstrations that model how enveloped and nonenveloped viruses are released from infected cells.

  • HIV Protease Inhibitors

    HIV Protease Inhibitors

    Activity

    This demonstration models how the HIV protease enzyme functions and how its activity is blocked by a class of anti-HIV drugs.

  • Viral DNA Integration

    Viral DNA Integration

    Activity

    In this hands-on activity, students model how a double-stranded DNA copy of the HIV genome is integrated into the host cell DNA.

  • HIV Reverse Transcription and AZT

    HIV Reverse Transcription and AZT

    Activity

    Students model how the anti-HIV drug AZT (azidothymidine) interferes with the process of viral replication.

  • HIV Receptors and Co-receptors

    HIV Receptors and Co-receptors

    Activity

    This demonstration models the first step of the HIV life cycle: the binding of HIV envelope proteins to receptors on human helper T cells.

  • Virus Explorer

    Virus Explorer

    Click & Learn

    Explore the similarities and differences of a variety of viruses by sorting them based on structure, genomic make-up, host range, transmission mechanism, and vaccine availability.

  • Dengue Virus Enters a Cell

    Dengue Virus Enters a Cell

    Animation

    (1 min 33 sec) Infection begins when the dengue virus uses receptors on an immune cell's surface to gain entry and release its genome.

  • Dengue Virus Life Cycle

    Dengue Virus Life Cycle

    Animation

    (4 min 12 sec) Dengue virus has sophisticated mechanisms for entering a cell, for replicating its RNA genome, and for translating proteins.

  • HIV life cycle

    HIV life cycle

    Animation

    (4 min 52 sec) How HIV infects a cell and replicates itself using reverse transcriptase and the host's cellular machinery.

  • AZT blocks reverse transcriptase

    AZT blocks reverse transcriptase

    Animation

    (1 min 46 sec) HIV's reverse transcriptase mistakes AZT for thymidine. Once incorporated, AZT stops reverse transcription.