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Regulation of the Lactase Gene

Summary

Lactase persistence results from a mutation that changes how transcription factors interact, thereby affecting gene expression.

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Mutations in DNA regions that control gene expression can alter the way genes are expressed. Lactase persistence is the trait that allows adults to continue to digest milk; it results from a mutation in an enhancer region of the lactase gene.

Also featured on the HHMI DVD Stones, Bones, and Genes: The Origins of Modern Humans, available free from HHMI.

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Additional Materials

Bulletin Article
Bulletin Article