More About PPAR-gamma Activation in the Fat Cell
The PPAR-gamma receptor activates certain genes in a fat cell, resulting in the storage of fat and changes in hormone levels. This animation includes audio narration: please make sure your computer's volume is up so that you can hear it.
PPAR-gamma Activation in the Fat Cell Background
PPAR-gamma is one of a family of receptors that is responsible for regulating the burning or storing of fat. Drugs can be designed to activate the PPAR-gamma receptor. Once activated, it in turn activates certain genes. The products of these genes cause the fat cell to store fat rather than release it into the body. This increase in stored fat also changes the levels of certain hormones released by the fat cell.
From Lecture Three of the 2004 Holiday Lectures Series "The Science of Fat."
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The 2004 Holiday Lectures Series "The Science of Fat"
PPAR-gamma Activation in the Fat Cell Credits
Director: Dennis Liu, Ph.D.
Scientific Direction: Ronald Evans, Ph.D.
Scientific Content: Satoshi Amagai, Ph.D.
Animator: Eric Keller