HomeHHMI's BioInteractiveModeling the Regulatory Switches of the Pitx1 Gene in Stickleback Fish

BioInteractive

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Classroom Resource
Modeling the Regulatory Switches of the Pitx1 Gene in Stickleback Fish

Summary

A hands-on activity in which students interpret molecular diagrams and build physical models of eukaryotic gene regulation.

A hands-on activity in which students interpret molecular diagrams and build physical models of eukaryotic gene regulation. Students will review eukaryotic gene transcription, explore how changes in gene expression can affect body development, and learn how those changes, with the appropriate selective pressure, play a role in the evolution of a population.

Appropriate for: high school biology (all levels), introductory college biology

Supporting Materials (5)

Short Film
After the end of the last ice age 10,000 years ago, populations of marine stickleback fish became stranded in freshwater lakes dotted throughout the Northern Hemisphere in places of natural beauty like Alaska and British Columbia. These remarkable little fish have adapted and thrive, living permanently in a freshwater environment drastically different than the ocean.
Film Guides
These classroom-ready resources complement the short film Evolving Switches, Evolving Bodies, which tells the story of the dramatic transformation of stickleback fish as they adapted to living in freshwater habitats drastically different from the ocean.
Classroom Resource
A hands-on activity in which students analyze the results of genetic crosses between stickleback fish with different traits.
Classroom Resource
A worksheet that guides students through The Stickleback Evolution Virtual Lab. The virtual lab lets students learn firsthand the methods for analyzing body structure in stickleback collected from lakes and fossils recovered from a quarry. Students measure, record, and graph their results to discover evolutionary patterns.
Virtual Lab
This virtual lab teaches skills of data collection and analysis to study evolutionary processes using stickleback fish and fossil specimens.

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