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Medicine in the Genomic Era

Summary

In the 2013 Holiday Lectures on Science, leading medical researchers explain how advances in genomics are revolutionizing their work, leading to a better understanding of disease and to improved treatments.

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Sixty years after James Watson and Francis Crick revealed the structure of the DNA double helix and only a decade after scientists published the first complete read-through of all three billion DNA bases in the human genome, the ability to routinely sequence and analyze individual genomes is revolutionizing the practice of medicine—from how diseases are first diagnosed to how they are treated and managed.

In the 2013 Holiday Lectures on Science, Charles L. Sawyers of Memorial Sloan-Kettering Cancer Center and Christopher A. Walsh of Boston Children’s Hospital will reveal the breathtaking pace of discoveries into the genetic causes of various types of cancers and diseases of the nervous system, and discuss the impact of those discoveries on our understanding of normal human development and disease.

In This Series (6)

by Christopher Walsh, MD PhD

Recent advances in DNA sequencing technology have led to a better understanding of the many genes that play a role in brain...

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by Charles Sawyers, MD

Understanding that cancer is caused by mutations in genes that regulate cell proliferation has led to the development of...

Read More › (Duration: 58 min 33 sec)
by Christopher Walsh, MD PhD

Over the past decade, the application of advanced DNA sequencing techniques has greatly increased our understanding of the...

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by Charles Sawyers, MD

Genetic data from a large number of tumor types reveal commonly mutated genes and uncover connections between different types...

Read More › (Duration: 58 min 46 sec)
by Elinor Karlsson, PhD

Dr. Elinor Karlsson discusses her work with dogs as a model organism for genomic studies.

Read More › (Duration: 28 min 54 sec)
by Charles Sawyers, MD and Christopher Walsh, MD PhD

A student discussion with the lecturers of the 2013 Holiday Lectures on Science.

Read More › (Duration: 37 min 26 sec)

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Sixty years after Watson and Crick revealed the structure of the DNA double helix, the ability to routinely sequence and analyze individual genomes is revolutionizing the practice of medicine.

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