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Learning from Patients: The Science of Medicine

Summary

As part of the 2003 Holiday Lectures on Science, Dr. Bert Vogelstein and Dr. Huda Y. Zoghbi discuss how their patients have led to a deeper understanding of the genetic and molecular bases of neurological disorders and cancer. Thanks to these patients, researchers can now apply the knowledge gained to diagnosis, prevention, and the search for cures.

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Biomedical scientists can gain essential insights from patients that help move their research in new directions. In four lectures, Dr. Bert Vogelstein and Dr. Huda Y. Zoghbi discuss how their patients have led them to a deeper understanding of the genetic and molecular bases of cancer and neurological disorders. Dr. Vogelstein explains our current understanding of the biology of cancer and how scientists are using information about cancer genes to treat and prevent the disease. Dr. Zoghbi recounts the research journeys she took to find the genes associated with two devastating neurological disorders: spinocerebellar ataxia type 1 and Rett syndrome.

Awards

  • 2004 Telly Awards; Silver

In This Series (5)

by Bert Vogelstein, MD

Although there are numerous kinds of cancer, all stem from alterations that allow cell division to outstrip cell demise.

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by Bert Vogelstein, MD

The identification of hundreds of genes involved in the formation and spread of cancer is leading to promising new methods for...

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by Huda Y. Zoghbi, MD

Mutations in key genes can lay waste to the nervous system. By studying large families predisposed to developing these genetic...

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by Huda Y. Zoghbi, MD

Girls with Rett syndrome develop normally for about 18 months and then begin to regress. With the help of affected girls and...

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by Bert Vogelstein, MD and Huda Y. Zoghbi, MD

Genetic research benefits health, but also raises thorny ethical issues.

Read More › (Duration: 39 min 44 sec)

Available for Order

DVD

In four lectures, Dr. Bert Vogelstein and Dr. Huda Y. Zoghbi discuss how their patients have led them to a deeper understanding of the genetic and molecular bases of cancer and neurological disorders.

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Additional Materials

Bulletin Article
Bulletin Article