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Of Hearts and Hypertension: Blazing Genetic Trails


In four lectures, Richard P. Lifton, MD, PhD, and Christine E. Seidman, MD, discuss their groundbreaking work in using genetic and molecular approaches to understand cardiovascular diseases.

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Scientists are gaining a greater understanding of the genetic and molecular bases of cardiovascular diseases, knowledge that can lead to new tests and therapies. In four lectures, Dr. Christian E. Seidman and Dr. Richard P. Lifton discuss their groundbreaking research. Dr. Seidman explains how heart circulation works and discusses her research in identifying the mutant genes that cause hypertrophic cardiomyopathy, the most common cause of sudden cardiac death in young athletes. Dr. Lifton discusses his work on the genetics of hypertension and other diseases affected by the kidney's ability to regulate salt. The lectures feature an animation on the anatomy of the human heart and questions from the student audience.


  • 1999 Aurora Gold Award

In This Series (4)

by Christine E. Seidman, MD

The heart acts as a dual pump, sending oxygen-depleted blood to the lungs to be reinvigorated and pumping oxygen-rich blood to...

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by Richard P. Lifton, MD, PhD

The discovery of DNA as the basis of heredity led to an explosive growth of knowledge about the human genome and allowed the...

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by Christine E. Seidman, MD

Although heart disease typically occurs after middle age, seemingly fit and healthy young individuals can die suddenly from...

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by Richard P. Lifton, MD, PhD

Molecular genetic approaches have identified genes that, when mutated, cause either increased or decreased blood pressure.

Read More › (Duration: 1 hr 3 sec)

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