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Heartbreak: Of Mutations and Maladies

Summary

Although heart disease typically occurs after middle age, seemingly fit and healthy young individuals can die suddenly from unrecognized heart disease.

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(Duration: 58 min 28 sec)

Although heart disease typically occurs after middle age, seemingly fit and healthy young individuals can die suddenly from unrecognized heart disease. In many cases, the culprit is hypertrophic cardiomyopathy, a disorder characterized by thickening of the ventricular muscle. It is caused by mutations in genes that encode proteins of the sarcomere, the contractile apparatus of muscle cells.

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