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BioInteractive

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DNA Sequence Assembly

Summary

Learn the principles of how DNA is sequenced and assembled into whole genomes using the Sanger method, shotgun sequencing, or ultra-deep sequencing.

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From 2000 to 2010, the speed of DNA seqeuencing increased 50,000-fold. Advancements in biochemical technology and bioinformatics fueled the phenomenal increase. This feature looks at a few key concepts to understand how this advancement came about.

Also featured on the HHMI DVD, Viral Outbreak: The Science of Emerging Disease, available free from HHMI. 

Download the accompanying worksheet (PDF) for students to complete as they go through the Click and Learn.

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