The lecturers, joined by Dr. Kay Jamison of the Johns Hopkins University School of Medicine and Dr. Gerald Fischbach of the Simons Foundation, answer questions concerning autism, manic depression, and other mental illnesses.
Mutations in key genes can lay waste to the nervous system. By studying large families predisposed to developing these genetic disorders, scientists can identify the responsible altered gene.
Girls with Rett syndrome develop normally for about 18 months and then begin to regress. With the help of affected girls and their families, Dr. Zoghbi and her collaborators searched for the gene responsible for this neurological disorder.
In the 2013 Holiday Lectures on Science, leading medical researchers explain how advances in genomics are revolutionizing their work, leading to a better understanding of disease and to improved treatments.
A brochure from the 2013 Holiday Lectures on Science.
Recent advances in DNA sequencing technology have led to a better understanding of the many genes that play a role in brain development.
Over the past decade, the application of advanced DNA sequencing techniques has greatly increased our understanding of the genetic basis of autism.