Doug Melton and Nadia Rosenthal are leaders in stem cell research, working primarily with mouse and human tissue. They will discuss where embryonic and adult stem cells come from and the biology of how they supply the cells the body needs.
An overview of embryonic development, the progressive differentiation of cells, and properties of embryonic stem cells.
In cloning, a cell's genetic machinery is reprogrammed. Can we similarly coax stem cells to become specific cell types?
To accompany the lecture series Potent Biology: Stem Cells, Cloning, and Regeneration.
To accompany the lecture series Evolution: Constant Change and Common Threads.
Normally the trillions of lymphocytes in the human body do not attack their host.
A group of 14 stink bug eggs attached to the underside of a poplar leaf.
Many animals have a third eyelid called a nictitating membrane that protects the eye.
The young starlet sea anemone forms tentacles by cell division, migration, and shape changes.
... but that's not all they'll do. Several genes determine the diverse shapes and functions of crustacean appendages.
Female peacock spiders stay with their young in an egg sac until they can fend for themselves.
Chromosomes change form as a cell divides to ensure that each daughter cell gets a full, intact copy of the genome.
The male peacock spider performs a spectacular dance to attract a mate—but the female is not always impressed.
Zebrafish blood is generated from stem cells located in the tail region of fish embryos and later from stem cells located in the kidney of the adult fish.
Two views of a late pupa of an unidentified midge species (family Chironomidae).
This short-tailed fruit bat embryo shows a pattern of bones in its limbs characteristic of all tetrapods: one bone, two bones, lots of bones, digits.
During the larval stage, the Nemertean worm develops inside a hollow sac from which the juvenile eventually emerges, rupturing the sac and then eating the remains.
A new technique tracks thousands of cells in the fruit fly (Drosophila) embryo during development.
The surface cells of tadpole embryos have cilia that move the water around them.
The early embryonic cells of the sand dollar are caught in the act of synchronized cell division.
Warthog mothers look after their young in small family groups.
A growth cone contacts a repellant molecule on another axon, collapses, and withdraws.
Dante is a 10-year-old boy born with hemimegalencephaly—an enlargement of half his brain.
A reduction in the level of sonic hedgehog (SHH) gene expression can lead to cyclopia.
A mini-documentary discussing the remarkable regenerative capabilities of the planarian, and how HHMI researcher Alejandro Sánchez Alvarado uses them to study the biology of stem cells.