A lesson that requires students to transcribe and translate portions of the wild-type and mutant rock pocket mouse Mc1r genes and compare sequences to identify the locations and types of mutations responsible for the coat color variation described in the film.
An advanced lesson that describes the role of mutations in the birth and death of genes. It includes background information, examples, video clips, and animations.
A hands-on activity that uses simulations with beads to teach students about population genetics, the Hardy-Weinberg principle, and how natural selection alters the frequency distribution of heritable traits.
A lesson that requires students to work through a series of questions pertaining to the genetics of sickle cell disease and its relationship to malaria. These questions will probe students' understanding of Mendelian genetics, probability, pedigree analysis, and chi-square statistics.
To accompany the lecture series Learning from Patients: The Science of Medicine.
A hands-on activity in which students analyze the results of genetic crosses between stickleback fish with different traits.
Students explore the genetic changes associated with lactose tolerance/intolerance and how the trait is inherited in families.
Topics include: DNA structure and function, DNA replication, damage to DNA and eukaryotic chromosomal structure.
Topics include: natural selection, artificial selection, population genetics, human adaptations and evolution, and phylogenetics.
These two hands-on activities are based on a Howard Hughes Medical Institute 2013 Holiday Lectures on Science video featuring researcher Dr. Charles L. Sawyers.
Construct evolutionary trees by sorting seashells. To accompany the lecture series Exploring Biodiversity: The Search for New Medicines and the Sorting Seashells Click and Learn interactive.
This activity can be used in conjunction with the short film The Double Helix. It introduces students to the classic experiment by Matthew Meselson and Franklin Stahl, which revealed that DNA replication follows the semiconservative model.