Prialt does not block the mammalian motor synapse, but blocks the pain pathway in the spinal cord.
Multiple cone snail toxins attack different molecules of the nervous system and cause paralysis.
Electrical and chemical signals are used by neurons to communicate with one another at contact points called synapses.
Genes associated with autism affect the structure and function of neuronal synapses.
The fetal brain grows enormously during pregnancy, both in terms of its size and the number of neurons it has.
Illustrates how providing leptin to an obese mouse rapidly rewires its hypothalamus neurons.
Some cone snail toxins chemically hyperactivate neurons and immobilize prey, much like a Taser.
Late LTP (long-term memory) involves dopamine activation of CREB to support new synaptic growth.
Early LTP (short-term memory) depends on a calcium-dependent protein kinase to strengthen an existing synapse.
Long-term memory requires the activation of CREB, turning on specific genes that support new synaptic growth.
Neurons in the cortical area 5 are active when a cat is straddling an obstacle.
Prialt, a drug derived from cone snail venom, paralyzes fish by blocking calcium channels at a motor synapse.
The growth cone of a neuron avoids repellant molecules and navigates to innervate the appropriate muscle.
Illustrates how studying one family's pedigree can reveal an entire history of passing on a genetic disorder such as SCA1.
Varying concentrations of a signaling molecule activate different transcription factors and determine cell fate.
A dramatic illustration of how hearing happens in the ear.