A visual representation of the U.S. AIDS epidemic from 1981 to 1997. Each dot represents 30 cases.
HIV's reverse transcriptase mistakes AZT for thymidine. Once incorporated, AZT stops reverse transcription.
Protease inhibitors prevent maturation of viral proteins inside HIV particles.
How a cell infected by a virus signals cytotoxic T lymphocytes to kill the cell before the virus replicates and spreads.
How HIV infects a cell and replicates itself using reverse transcriptase and the host's cellular machinery.
Adam Barrett describes his seven-drug antiretroviral regimen and the importance of adherence.
An interview with Kwame Atsina, an undergraduate who discusses what it's like to be in a lab doing scientific research.
Adam Barrett, a nurse who is HIV positive, discusses his first symptoms and the challenges of adhering to a drug regimen.
Zinhle Thabethe describes how antiretroviral therapy has changed her life.
An interview with Silvia Caballero, an undergraduate who discusses what it's like to be in a lab doing scientific research.
Video microscopy of a cytotoxic T lymphocyte in action.
Using tic tac mints as anti-HIV drug stand-ins, students experience the challenges of adhering to an antiretroviral regimen.
A live demonstration of how a rapid antibody-based HIV test works.
Catherine Gaynes, an HIV-positive patients, discusses her HIV diagnosis, how her family reacted, and avoiding HIV infection.
Dr. Michael Gottlieb was the first physician to notice the new disease of AIDS.
Dr. Beatrice Hahn's research has traced the origin of HIV to chimpanzees in Cameroon.
Dr. Beatrice Hahn discusses how HIV originated in Africa by cross-species transmission from chimpanzees to humans.
An interview with Tobi Ogbechie, an undergraduate who discusses what it's like to be in a lab doing scientific research.
An interview with Dr. Ojikutu.
When parents die of AIDS, the orphans often go to live with a "gogo," the Zulu word for grandmother.
How a South African hospital is coping with the HIV/AIDS epidemic and its many related healthcare issues.
Doctors hope to encourage healers to direct their patients to clinics for TB and AIDS-related diseases.
A glimpse of the TB ward at a South African hospital, illustrating an illness associated with the AIDS epidemic.
A program designed to provide health care and housing to South Africans living in poverty.
Using soccer to teach children how to make important life choices and how to avoid HIV infection.
Adam Barrett remembers his symptoms of acute HIV infection.
An interview with Dr. Walker.
An interview with Katie Walter, an undergraduate who discusses what it's like to be in a lab doing scientific research.
Why has it been so hard to develop a vaccine against HIV? How are new medicines revolutionizing AIDS treatment? Can AIDS be cured?
The genesis of AIDS, identifying HIV as the virus that causes AIDS, and the modern global epidemic.
The HIV life cycle, and how the virus destroys the immune system's ability to respond to infection.
Treating HIV infection with antiretroviral therapy, and HIV's ability to develop drug resistance.
The search for an effective HIV vaccine, and advances in genomics that may lead to a breakthrough.
A discussion with three students who are helping in the global fight against HIV and AIDS.
Three HIV-positive individuals share their personal experiences about living with HIV.
An overview of the immune system, concentrating on the roles played by B and T lymphocytes, and the antigen-presentation system.
A brief discussion of what makes a virus a retrovirus, and how they differ from other types of viruses.
Problems associated with adherence to antiviral drugs, and a student activity that mimics adherence to a multi-drug regimen.
To accompany the lecture series AIDS: Evolution of an Epidemic. In this activity, you simulate taking HIV antiretroviral drugs by using tic tac mints and Kool-Aid packets.
A text transcript of the 2007 Holiday Lectures on Science, AIDS: Evolution of an Epidemic.
A chapter list to accompany the DVD.
The poster from the 2007 Holiday Lectures on Science, AIDS: Evolution of an Epidemic. It shows each stage of the HIV life cycle and highlights points in the cycle that have been targeted by anti-retroviral drugs.