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Showing 1 - 100 of 608 results
Classroom Resource
To accompany the lecture series Changing Planet: Past, Present, Future. Using an online calculator, you will estimate your household’s carbon footprint and explore various actions to reduce it.
Classroom Resource
To accompany the lecture series Potent Biology: Stem Cells, Cloning, and Regeneration.
Classroom Resource
Construct evolutionary trees by sorting seashells. To accompany the lecture series Exploring Biodiversity: The Search for New Medicines and the Sorting Seashells Click and Learn interactive.
Classroom Resource
To accompany the lecture series Evolution: Constant Change and Common Threads.
Classroom Resource
To accompany the lecture series Evolution: Constant Change and Common Threads.
Classroom Resource
EarthViewer was designed as an interactive learning tool. Download the PDF linked in the right hand column for some ideas on how to use the app in your class, or click on the EarthViewer link to find out more about the app.
Classroom Resource
This guide correlates all the resources available on the Holiday Lectures on Science DVDs and throughout the BioInteractive.org website to specific Big Ideas, Enduring Understandings, and Essential Knowledge threads of the new AP® Biology Curriculum Framework.
Classroom Resource
Topics include: PCR, DNA Sequencing, Genetic Engineering, and Microarray. This guide includes multiple classroom-ready worksheets to accompany HHMI’s virtual labs.
Classroom Resource
Topics include: DNA structure and function, DNA replication, damage to DNA and eukaryotic chromosomal structure.
Classroom Resource
Topics include: natural selection, artificial selection, population genetics, human adaptations and evolution, and phylogenetics.
Classroom Resource
Topics include: Gene expression, RNA structure and function, transcription, RNA processing, translation, and post-translational events.
Classroom Resource
Topics include: Gene regulation mechanisms and examples, gene regulation and human disease, and RNA interference.
Classroom Resource
Topics include: Immunology, HIV immune response and drug development, ELISA, CCR5 co-receptor mutation, vaccine development, dengue fever, and immunological response
Classroom Resource
A poster from the 2012 Holiday Lectures on Science, Changing Planet: Past, Present, Future. It details the importance of foraminifera, known as "forams" for short, in discovering significant changes in Earth's past.
Classroom Resource
A poster from the 2012 Holiday Lectures on Science, Changing Planet: Past, Present, Future. It shows the different organisms and metabolic diversity that results in a miniature model called a Winogradsky column.
Classroom Resource
A poster from the 2012 Holiday Lectures on Science, Changing Planet: Past, Present, Future. It illustrates how the Earth has evolved over the past 4.6 billion years, and highlights how that evolution influences biological evolution.
Classroom Resource
The poster from the 2011 Holiday Lectures on Science, Bones, Stones and Genes: The Origin of Modern Humans. It provides a unique look at the classic "tree of life" and features a timeline of various hominid fossils and their stone tool usage.
Classroom Resource
The poster from the 2010 Holiday Lectures, Viral Outbreak: The Science of Emerging Disease, illustrating the size, geometry, and different classifications of viruses.
Classroom Resource
The poster from the 2008 Holiday Lectures on Science, Making Your Mind: Molecules, Motion, and Memory. It illustrates the structure and function of a neuron, including how it transmits electrical and chemical signals.
Classroom Resource
The poster from the 2007 Holiday Lectures on Science, AIDS: Evolution of an Epidemic. It shows each stage of the HIV life cycle and highlights points in the cycle that have been targeted by anti-retroviral drugs.
Classroom Resource
The poster from the 2005 Holiday Lectures on Science, Evolution: Constant Change and Common Threads. Place the fossils in the right geological era, period, and epoch.
Classroom Resource
The following classroom-ready resources complement The Making of the Fittest: Natural Selection and Adaptation, which describes the physical and genetic evolutionary changes in rock pocket mouse populations.
Classroom Resource
The following classroom-ready resources complement The Making of the Fittest: Natural Selection in Humans, which describes the connection between malaria and sickle cell anemia—one of the best-understood examples of natural selection in humans.
Classroom Resource
The following classroom-ready resources complement The Day the Mesozoic Died, which tells the story of the extraordinary detective work that led to the stunning discovery that an asteroid struck Earth 66 million years ago, triggering a mass extinction of animals, plants and even microorganisms.
Classroom Resource
The following classroom-ready resources complement Evolving Switches, Evolving Bodies, which tells the story of the dramatic transformation of stickleback fish as they adapted to living in drastically different environments. Scientists have studied both living and fossil stickleback populations,...
Classroom Resource
The following classroom-ready resources complement The Making of the Fittest: The Birth and Death of Genes, which describes how scientists have pieced together the evolutionary history of the Antarctic icefish. The icefish makes an excellent case study for genetic evolution as both the gain and...
Short Film
Scientists have pieced together the evolutionary history of the Antarctic icefish. The icefish makes an excellent case study for genetic evolution as both the gain and loss of genes have led to key adaptations.
Lectures
Students discuss the short film after a screening at the 2012 Holiday Lectures on Science.
Click & Learn
Take this quiz to see how well you understand some of the topics covered in the 1999 Holiday Lectures on infectious disease.
Click & Learn
Explore principles of taxonomy by sorting seashells according to their morphological characteristics and constructing an evolutionary tree.
Animation
HIV's reverse transcriptase mistakes AZT for thymidine. Once incorporated, AZT stops reverse transcription.
Animation
Of the 3 billion letters in the human genome, only 1% directly code for proteins. Of the rest, about 25% make up genes and their regulatory elements. The functions of the remaining letters are still unclear.
Animation
Reactive molecules, such as free radicals, and solar ultraviolet radiation can lead to mutations in DNA. Most mutations are corrected, but in rare cases mutations can accumulate and cause diseases such as cancer.
Interview
A graduate student in the Knoll lab, Ms. Creveling explains how she selects field sites, and what sparked her interest in geology.
Interview
A graduate student in the Schrag lab, Mr. Laakso uses computer modeling of Earth's atmosphere to help predict changes to come.
Animation
DNA has a double helix structure. If untwisted, DNA looks like two parallel strands. Each strand has a linear sequence of A, C, G, and T. The precise order of the letters carries the coded instructions. One strand is a complementary image of the other: A always pairs with T, and C always pairs...
Click & Learn
Learn about how gene switches can control expression of genes in different tissues.
Interview
An interview with Dr. Michael McIntosh, who discovered the drug Prialt while working as an undergraduate in Dr. Olivera's lab.
Interview
An interview with Dr. Audra Pompeani, a graduate student in Bonnie Bassler's lab.
Interview
An interview with Dr. Lee Swem, a post-doctoral fellow in Bonnie Bassler's lab.
Video Clips
Dr. Vogelstein shows video taken during a colonoscopy and the removal of a polyp.
Interview
An interview with Harith Rajagopalan, a scientist in Dr. Vogelstein's lab.
Short Film
The rock pocket mouse is a living example of Darwin’s process of natural selection.
Short Film
In some parts of the world, there is an intimate connection between the infectious parasitic disease malaria and the genetic disease sickle cell anemia.
Click & Learn
Comparing features of a 4.4-million-year-old fossil skeleton to those of human and chimpanzee skeletons sheds light on our evolutionary history.
Click & Learn
This survey, developed by Horne and Ostberg, will let you determine if you are a morning or an evening person.
Click & Learn
Answer the questions in this online quiz to test your knowledge of what determines the sex of a human, a fruit fly, and a snapping turtle.
Click & Learn
Paleoanthropology provides an excellent example of the scientific process at work.
Click & Learn
Learn about the nature of vector-borne diseases, and the life cycle of the dengue vector mosquito.
Click & Learn
Answer interactive questions to explore the logic of the Virochip microarray design, particularly how evolutionary relationships can be used to detect new viruses.
Click & Learn
Explore the biology of the symbiotic relationship between the Hawaiian Bobtail squid and bioluminescent bacteria Vibrio fischeri.
Click & Learn
Understand how quorum sensing works by reasoning through experiments involving genetically-engineered bioluminescent bacteria.
Click & Learn
Learn why verifying a person's gender may be harder than you think.
Click & Learn
How both gene chips and microarray slides are created.
Click & Learn
Small molecules are chemicals that can interact with proteins to affect their functions. Learn about the structure and biological functions of various small molecules like sugar and caffeine.
Click & Learn
Different gaits employed by animals and how the nervous system is able to switch between them.
Click & Learn
Measuring neuronal activity, generating action potentials, and recording the firing of individual neurons.
Click & Learn
A brief discussion of what makes a virus a retrovirus, and how they differ from other types of viruses.
Click & Learn
Problems associated with adherence to antiviral drugs, and a student activity that mimics adherence to a multi-drug regimen.
Click & Learn
An overview and comparison of different regenerative capabilities in many different organisms.
Click & Learn
Learn about the different ways scientists are able to detect when genes are being expressed in various tissues.
Click & Learn
RNA is an information molecule that can also function as an enzyme. Learn about the many different forms that RNA can take.
Click & Learn
This mini-lesson covers the research on telomeres that has happened since the 1995 Holiday Lectures.
Click & Learn
There is no way to directly measure how much fat a living person has. Learn about the various methods used by researchers and fitness advisors to estimate a person’s body fat.
Click & Learn
This slide show delves into the various molecular shapes that fat can take.
Click & Learn
This slide show explores some of the ways the body processes fat, including digestion, transport, conversion, and energy extraction.
Click & Learn
Learn about the structure and function of this fascinating cellular machine.
Click & Learn
DNA microarrays, or gene chips, are an important new technology for genomic research. Learn how researchers use computing to analyze and interpret the huge datasets generated by microarray experiments.
Click & Learn
All living humans originated from populations of ancestors who migrated out of Africa less than 100,000 years ago. Learn how scientists have used genetic markers to trace the migration routes and origins of modern human populations.
Article
Cancer occurs when a single cell acquires the ability to reproduce aggressively and to invade other tissues. Left unchecked, this anarchy destroys the cellular society. It interferes with the body's normal function, destroys organs, and eventually kills the organism.
Article
From the inheritance of acquired traits to natural selection to evo devo, evolutionary theory has itself evolved.
Classroom Resource
A short article by Dr. Sean B. Carroll detailing the discoveries covered in the film The Day The Mesozoic Died.
Classroom Resource
A lesson in which students analyze the chemical data that led researchers to conclude that the K-T boundary layer contained an extraordinary concentration of iridium.
Classroom Resource
A lesson in which students read a passage and answer questions about the information presented, testing their non-fiction reading comprehension.
Classroom Resource
A worksheet in which students calculate how much iridium was released, and eventually deposited all over the Earth, by the impact of the asteroid that caused the K-T extinction.
Classroom Resource
A hands-on activity in which students see first-hand the difference in foraminifera fossils below and above the K-T boundary.
Classroom Resource
A data collection and analysis lesson that examines selection for coat color in pocket mouse populations on different color substrates over time.
Classroom Resource
A lesson that uses real rock pocket mouse data collected by Dr. Michael Nachman and his colleagues to illustrate the Hardy-Weinberg principle.
Classroom Resource
A lesson that requires students to transcribe and translate portions of the wild-type and mutant rock pocket mouse Mc1r genes and compare sequences to identify the locations and types of mutations responsible for the coat color variation described in the film.
Classroom Resource
An advanced lesson that requires students to analyze partial DNA sequences of the Mc1r gene and identify the effects of mutations on the MC1R protein pathway.
Classroom Resource
An activity in which students analyze amino acid data and draw conclusions about the evolution of coat color phenotypes in different rock pocket mouse populations.
Classroom Resource
A worksheet in which students write down the evidence that led to the discovery that an asteroid struck Earth about 66 million years ago, causing a mass extinction.
Classroom Resource
A simple activity that investigates the importance of antifreeze proteins to icefish survival.
Classroom Resource
An advanced lesson that describes the role of mutations in the birth and death of genes. It includes background information, examples, video clips, and animations.
Classroom Resource
A simple demonstration that uses readily-available materials to simulate how blood pumps through the circulatory system of icefish and other fish.
Classroom Resource
A dramatic demonstration that simulates how tiny ice crystals would form and grow in the blood of most fish if they ventured into the icy waters of the Antarctic.
Classroom Resource
A worksheet designed to show students how scientists make their discoveries. It provides students with background information about how Dr. Allison's work built upon the contributions made by other scientists.
Classroom Resource
A worksheet designed to actively engage students as they watch the film. Students are asked to answer questions pertaining to the information provided in the film.
Classroom Resource
A hands-on activity in which students construct models of sickle-cell hemoglobin fibers inside red blood cells to illustrate how changes in the structure of a protein can affect cell shape. Students are then asked to relate these changes to disease symptoms.
Classroom Resource
A hands-on activity that uses simulations with beads to teach students about population genetics, the Hardy-Weinberg principle, and how natural selection alters the frequency distribution of heritable traits.
Classroom Resource
A lesson that requires students to work through a series of questions pertaining to the genetics of sickle cell disease and its relationship to malaria. These questions will probe students' understanding of Mendelian genetics, probability, pedigree analysis, and chi-square statistics.
Classroom Resource
To accompany the lecture series Evolution: Constant Change and Common Threads.
Classroom Resource
To accompany the lecture series Making Your Mind: Molecules, Motion, and Memory.
Classroom Resource
To accompany the lecture series AIDS: Evolution of an Epidemic. In this activity, you simulate taking HIV antiretroviral drugs by using tic tac mints and Kool-Aid packets.
