The PPAR-gamma receptor activates certain genes in a fat cell, resulting in the storage of fat and changes in hormone levels.
The PPAR-delta receptor activates certain genes in a muscle cell, resulting in the burning of fat.
Comparison of the change in BMI for a given height and varying weights.
An overview of how dietary fat gets digested, packaged, and sent to various tissues for storage or energy.
A timeline illustrating the gradual effects of obesity on the body, including diabetes, atherosclerosis, and heart attack.
A 3-D animation that shows how plaques form in a blood vessel, leading to blockage and a heart attack.
A 3-D animation that shows the location of the hypothalamus in a mouse's brain.
Demonstrates how changes in the amount of fat tissue lead to changes in leptin levels and thus changes in appetite.
Illustrates how providing leptin to an obese mouse rapidly rewires its hypothalamus neurons.