Delivering a single virus to a cell allows the virus to infect the cell, replicate, and give rise to many progeny viruses. These viruses can then infect many neighboring cells.
The geometric structures of viruses are beautiful and can be used, along with genomic information, to identify them.
A visual representation of the U.S. AIDS epidemic from 1981 to 1997. Each dot represents 30 cases.
HIV's reverse transcriptase mistakes AZT for thymidine. Once incorporated, AZT stops reverse transcription.
When two different strains of influenza infect a single cell, their genetic material can mix freely, resulting in a new third strain of influenza.
Dengue virus has sophisticated mechanisms for entering a cell, for replicating its RNA genome, and for translating proteins.
The dengue virus's outer envelope proteins form symmetrical units and overlay the lipid envelope, capsid, and the RNA genome.
Infection begins when the dengue virus uses receptors on an immune cell's surface to gain entry and release its genome.
How HIV infects a cell and replicates itself using reverse transcriptase and the host's cellular machinery.
Adam Barrett describes his seven-drug antiretroviral regimen and the importance of adherence.
Adam Barrett, a nurse who is HIV positive, discusses his first symptoms and the challenges of adhering to a drug regimen.
Charles Runckel, a graduate student in the DeRisi lab, uses the Virochip to examine the mystery of bee colony collapse disorder.
Zinhle Thabethe describes how antiretroviral therapy has changed her life.
Catherine Gaynes, an HIV-positive patients, discusses her HIV diagnosis, how her family reacted, and avoiding HIV infection.
Dr. Beatrice Hahn's research has traced the origin of HIV to chimpanzees in Cameroon.
Dr. Beatrice Hahn discusses how HIV originated in Africa by cross-species transmission from chimpanzees to humans.
To prevent mosquitoes from spreading diseases, it's essential to understand their life cycle.
Reggaeton, a popular Latin music form, rallies against dengue.
Dr. Finlay and Dr. Richard Ganem use physical analogies to compare the size of bacteria and viruses relative to a standard mammalian cell.
Adam Barrett remembers his symptoms of acute HIV infection.
Watch two leading virus researchers explain how they use both simple and sophisticated technologies to detect and fight infectious agents.
Learn about research aimed at thwarting dengue fever in the lab and in communities.
New technologies like the Virochip harness DNA's properties to identify and fight new viruses.
Understanding the immune response is essential to developing safe vaccines for dengue and other diseases.
The SARS epidemic was successfully halted by a global research effort to identify a new virus.