Clive Wearing has lost his ability to remember and lives in a perpetual state of having just awoken.
What is mind? Can molecular biology help us understand mental function?
The history of localization of function in the brain, and research that led to the understanding of localization of memory.
How a nerve cell gets its identity, sends axons, and makes connections with other cells.
The cellular and molecular nature of learning and memory, investigated in simpler sea slugs and more-complex mice.
The lecturers, joined by Dr. Kay Jamison of the Johns Hopkins University School of Medicine and Dr. Gerald Fischbach of the Simons Foundation, answer questions concerning autism, manic depression, and other mental illnesses.
Mutations in key genes can lay waste to the nervous system. By studying large families predisposed to developing these genetic disorders, scientists can identify the responsible altered gene.
Girls with Rett syndrome develop normally for about 18 months and then begin to regress. With the help of affected girls and their families, Dr. Zoghbi and her collaborators searched for the gene responsible for this neurological disorder.
Dr. Friedman shows how leptin rewires neural circuits, and how population studies may identify obesity genes.
Dr. Joseph Takahashi takes us on an exciting journey into a very special region of the brain—the biological clock that governs our physiology and certain behaviors.
To accompany the lecture series Making Your Mind: Molecules, Motion, and Memory.
In the 2013 Holiday Lectures on Science, leading medical researchers explain how advances in genomics are revolutionizing their work, leading to a better understanding of disease and to improved treatments.
The poster for the 2013 Holiday Lectures on Science, Medicine in the Genomic Era, illustrates the difference between germline and somatic cell mutations.
One approach to understanding the brain is to reconstruct the shapes and connections of individual neurons.
The developing brain needs a constant source of new cells as it builds the circuits that will control behavior.
Recent advances in DNA sequencing technology have led to a better understanding of the many genes that play a role in brain development.
Over the past decade, the application of advanced DNA sequencing techniques has greatly increased our understanding of the genetic basis of autism.
A student discussion with the lecturers of the 2013 Holiday Lectures on Science.
Dr. Walsh recalls his childhood as one of eight siblings, discovering science in college, and the role of genomics in studying autism.
Ms. Yang describes what it was like growing up in a family filled with medical doctors, discusses her MD-PhD program, and provides advice to high school students interested in science.
A unique group of cells in the eye’s retina specifically detects the upward motion of objects, such as a ball thrown in the air or…fireworks.
A new technique for making the brain transparent provides extremely detailed views of groups of neurons.
Even though Clive Wearing cannot remember people or events, his piano-playing skills are intact.
Dante is a 10-year-old boy born with hemimegalencephaly—an enlargement of half his brain.
Dr. Walsh is an HHMI investigator whose research focuses on understanding the genes involved in the development and function of the human brain.