HIV's reverse transcriptase mistakes AZT for thymidine. Once incorporated, AZT stops reverse transcription.
How HIV infects a cell and replicates itself using reverse transcriptase and the host's cellular machinery.
Zinhle Thabethe describes how antiretroviral therapy has changed her life.
Dr. Beatrice Hahn's research has traced the origin of HIV to chimpanzees in Cameroon.
Why has it been so hard to develop a vaccine against HIV? How are new medicines revolutionizing AIDS treatment? Can AIDS be cured?
The genesis of AIDS, identifying HIV as the virus that causes AIDS, and the modern global epidemic.
The HIV life cycle, and how the virus destroys the immune system's ability to respond to infection.
Treating HIV infection with antiretroviral therapy, and HIV's ability to develop drug resistance.
The search for an effective HIV vaccine, and advances in genomics that may lead to a breakthrough.
In four presentations, Donald E. Ganem, MD, and B. Brett Finlay, PhD, discuss the latest advances in understanding how pathogens invade the body and how this knowledge is leading to the development of new therapies. They also explain how new infectious diseases are recognized and how epidemics...
Dr. Donald Ganem describes how epidemiologists, physicians, and microbiologists work together to identify and study pathogens.
Dr. Ganem analyses the complex causes of epidemics—how changes in the environment and in human social behavior can give rise to new infectious diseases.
West Nile virus infects mosquitoes, birds, and people—with very different consequences.
Problems associated with adherence to antiviral drugs, and a student activity that mimics adherence to a multi-drug regimen.
A 3D model of the dengue virus reveals a shape like a soccer ball with an outer coating of glycoproteins.
A germ-spreading sneeze unleashes a shower of large liquid droplets and a moist gas cloud of smaller ones.
The measles virus can spread easily among people who have no immunity against it, as the current outbreak shows.