This animation shows how the random deactivation of one of the X chromosomes in a pair can lead to a mozaicism in the expression genes.
Quorum sensing regulates gene expression by a protein phosphorylation cascade that controls transcription.
The PPAR-delta receptor activates certain genes in a muscle cell, resulting in the burning of fat.
In the stickleback fish, pelvic-fin reduction resulted from changes in the regulatory switch elements of the Pitx1 gene. In the marine ancestor, the Pitx1 gene is activated in the pelvic-fin region during development to generate the fin. In the pelvic-reduced stickleback, the...
This animation shows how the protein MECP2, in conjuction with another protein complex, can act as an "on-off' switch for gene expression.
This animation shows the molecular interactions involved in the negative feedback loop responsible for circadian rhythms in mammals.
General transcription factors, activators, and repressors interact to regulate the transcription of eukaryotic DNA into RNA.
Watch these animations display the dynamic orchestration of the molecular events of the Drosophila biological clock.
Single-molecule analysis using super-resolution microscopes reveals that transcription factors are not usually found bound to their binding sites on DNA.