This animation illustrates how mistakes made during DNA replication are repaired.
DNA's chemical properties can be harnessed for a variety of biotechnology applications.
DNA has a double helix structure. If untwisted, DNA looks like two parallel strands. Each strand has a linear sequence of A, C, G, and T. The precise order of the letters carries the coded instructions. One strand is a complementary image of the other: A always pairs with T, and C always pairs...
The structure of DNA, discovered by James Watson and Francis Crick, suggests a mechanism of replication. The double helix unwinds, and each strand acts as a template for the construction of the new DNA molecule.
Using information from molecular research, this 3-D animation shows how DNA is replicated at the molecular level. It involves an enzyme that unwinds the DNA, and other enzymes that copy the two resulting strands.
Both strands of the DNA double helix act as templates for the new DNA strands. Incoming DNA is unraveled by the enzyme helicase, resulting in the 3' strand and the 5' strand. The 3' strands and the 5' strands are replicated by a DNA polymerase enzyme but in different ways.
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Dr. Eric Lander takes us on a tour of this remarkable genetic century, describing the rapid advances in DNA sequencing technologies and information science.
Dr. Lander explores human genetic variation and how it may affect individual susceptibility to certain diseases.
Interactively explore topics in biology with the Click and Learn app. Now available from the Apple App Store,...
This activity can be used in conjunction with the short film The Double Helix. It introduces students to the classic experiment by Matthew Meselson and Franklin Stahl, which revealed that DNA replication follows the semiconservative model.
Topics include: DNA structure and function, DNA replication, damage to DNA and eukaryotic chromosomal structure.