Mutations in key genes can lay waste to the nervous system. By studying large families predisposed to developing these genetic disorders, scientists can identify the responsible altered gene.
Girls with Rett syndrome develop normally for about 18 months and then begin to regress. With the help of affected girls and their families, Dr. Zoghbi and her collaborators searched for the gene responsible for this neurological disorder.
Dr. Friedman shows how leptin rewires neural circuits, and how population studies may identify obesity genes.
Recent advances in DNA sequencing technology have led to a better understanding of the many genes that play a role in brain development.
Over the past decade, the application of advanced DNA sequencing techniques has greatly increased our understanding of the genetic basis of autism.
Dr. Christopher Walsh discusses how genomic science has made enormous contributions to our understanding of the genetic causes of autism.
Dante is a 10-year-old boy born with hemimegalencephaly—an enlargement of half his brain.