One of the failed hypothetical models of DNA is Linus Pauling's triple helix model. This structure would be unstable under normal cellular conditions.
During the process of trying to elucidate the structure of DNA, Jim Watson made some cardboard models to try to understand how DNA nucleotides are paired. It helped him visualize how hydrogen atoms of paired nucleotides interact with each other to form a symmetrical structure that fits the...
Dr. Michael Gottlieb was the first physician to notice the new disease of AIDS.
Dr. Kandel illustrates the practice of the now-debunked theory of phrenology.
How has the amazing diversity of plants and animals evolved? What can fossils, butterflies, and stickleback fish tell us about the deep common ancestry of all living forms?
How Darwin came to publish The Origin of Species, and examples of how quickly evolution can change a population.
The genesis of AIDS, identifying HIV as the virus that causes AIDS, and the modern global epidemic.
Dr. Donald Ganem describes how epidemiologists, physicians, and microbiologists work together to identify and study pathogens.
What is mind? Can molecular biology help us understand mental function?
The history of localization of function in the brain, and research that led to the understanding of localization of memory.
Scientists have pieced together the evolutionary history of the Antarctic icefish. The icefish makes an excellent case study for genetic evolution as both the gain and loss of genes have led to key adaptations.
A short article by Dr. Sean B. Carroll detailing the discoveries covered in the film The Day The Mesozoic Died.
The following classroom-ready resources complement The Making of the Fittest: The Birth and Death of Genes, which describes how scientists have pieced together the evolutionary history of the Antarctic icefish. The icefish makes an excellent case study for genetic evolution as...
The following classroom-ready resources complement The Making of the Fittest: Natural Selection in Humans, which describes the connection between malaria and sickle cell anemia—one of the best-understood examples of natural selection in humans.
A worksheet designed to show students how scientists make their discoveries. It provides students with background information about how Dr. Allison's work built upon the contributions made by other scientists.
A worksheet designed to actively engage students as they watch the film. Students are asked to answer questions pertaining to the information provided in the film.
Has Earth changed over deep time? How did Earth shape life and life shape Earth? What does Earth's climate in the distant past tell us about the future?
The theory of plate tectonics took many decades to become accepted. The process by which it was finally accepted provides a fascinating glimpse into how scientists build new scientific consensus.
Scientific evidence for global climate change is overwhelming, yet the American public remains skeptical. History provides insights into how a Cold War-era think tank became an influential source of anti-regulation sentiment.
Students discuss the short film after a screening at the 2012 Holiday Lectures on Science.
Continents rose in elevation after ice sheets from the last ice age retreated. This suggested that the underlying mantle is pliable.
The concept that continents float on a pliable mantle is an important element of the theory of continental drift.
Dr. Oreskes explains her switch from research science to science history, and what led her to write Merchants of Doubt...
An early model of continental drift proposed that parts of continental plates can sink into the mantle, allowing for movement.
An early continental drift model proposed that mantle convection can produce continental movement and new plate formation.