Delivering a single virus to a cell allows the virus to infect the cell, replicate, and give rise to many progeny viruses. These viruses can then infect many neighboring cells.
The geometric structures of viruses are beautiful and can be used, along with genomic information, to identify them.
A visual representation of the U.S. AIDS epidemic from 1981 to 1997. Each dot represents 30 cases.
HIV's reverse transcriptase mistakes AZT for thymidine. Once incorporated, AZT stops reverse transcription.
When two different strains of influenza infect a single cell, their genetic material can mix freely, resulting in a new third strain of influenza.
Dengue virus has sophisticated mechanisms for entering a cell, for replicating its RNA genome, and for translating proteins.
The dengue virus's outer envelope proteins form symmetrical units and overlay the lipid envelope, capsid, and the RNA genome.
Infection begins when the dengue virus uses receptors on an immune cell's surface to gain entry and release its genome.
How HIV infects a cell and replicates itself using reverse transcriptase and the host's cellular machinery.
Adam Barrett describes his seven-drug antiretroviral regimen and the importance of adherence.
Adam Barrett, a nurse who is HIV positive, discusses his first symptoms and the challenges of adhering to a drug regimen.
Watch two leading virus researchers explain how they use both simple and sophisticated technologies to detect and fight infectious agents.
Learn about research aimed at thwarting dengue fever in the lab and in communities.
New technologies like the Virochip harness DNA's properties to identify and fight new viruses.
Understanding the immune response is essential to developing safe vaccines for dengue and other diseases.
The SARS epidemic was successfully halted by a global research effort to identify a new virus.
This discussion from the 2010 Holiday Lectures on Science explores the ethics of genetically-modified organisms and other topics.
Why has it been so hard to develop a vaccine against HIV? How are new medicines revolutionizing AIDS treatment? Can AIDS be cured?
The genesis of AIDS, identifying HIV as the virus that causes AIDS, and the modern global epidemic.
The HIV life cycle, and how the virus destroys the immune system's ability to respond to infection.
Treating HIV infection with antiretroviral therapy, and HIV's ability to develop drug resistance.
The search for an effective HIV vaccine, and advances in genomics that may lead to a breakthrough.
A discussion with three students who are helping in the global fight against HIV and AIDS.
Dr. Donald Ganem describes how epidemiologists, physicians, and microbiologists work together to identify and study pathogens.
Dr. Ganem analyses the complex causes of epidemics—how changes in the environment and in human social behavior can give rise to new infectious diseases.