This animation demonstrates how cancerous cells could be destroyed using a modified virus.
Quorum sensing regulates gene expression by a protein phosphorylation cascade that controls transcription.
The PPAR-gamma receptor activates certain genes in a fat cell, resulting in the storage of fat and changes in hormone levels.
A 3D animation showing the molecule p53 binds to DNA and initiates the transcription of mRNA.
This animation shows how the protein MECP2, in conjuction with another protein complex, can act as an "on-off' switch for gene expression.
This animation shows the molecular interactions involved in the negative feedback loop responsible for circadian rhythms in mammals.
How a cell infected by a virus signals cytotoxic T lymphocytes to kill the cell before the virus replicates and spreads.
Cytoplasmic factors play a significant part in determining how a cell develops. This segment discusses their importance in turning the appropriate genes on and off for proper development.
Dengue virus has sophisticated mechanisms for entering a cell, for replicating its RNA genome, and for translating proteins.
General transcription factors, activators, and repressors interact to regulate the transcription of eukaryotic DNA into RNA.
Watch these animations display the dynamic orchestration of the molecular events of the Drosophila biological clock.
A single transcription factor controls this operon, which contains five genes necessary to produce bioluminescence.
“The Assemblers” (Peter Skewes-Cox and Dr. Graham Ruby) sing about DNA and proteins.
How a nerve cell gets its identity, sends axons, and makes connections with other cells.
An overview of embryonic development, the progressive differentiation of cells, and properties of embryonic stem cells.
The role of stem cells in regeneration, and ongoing research to improve mammalian regeneration potency.
Dr. Evans reviews how PPARs regulate body weight by controlling whether fat is burned or stored.
Dr. Barbara Meyer explains the value of studying model organisms and introduces the nematode C. elegans.
Having too many chromosomes can lead to too much gene expression. Dr. Meyer explains how the gene that controls dosage compensation in C. elegans works.
Four lectures highlight the research of two scientists who have made groundbreaking discoveries elucidating the molecular basis of circadian clocks—the internal timekeepers that govern fluctuations in behavior and physiology on a 24-hour cycle.
Although tiny in size, the fruit fly has had a major impact on our understanding of circadian rhythms.
Dr. Rosbash discloses how scientists have persuaded Mother Nature to reveal the inner workings of the fruit fly's biological clock.
Dr. Takahashi describes the powerful strategies that he and others have harnessed for understanding biological clocks in mammals.
After the end of the last ice age 10,000 years ago, populations of marine stickleback fish became stranded in freshwater lakes dotted throughout the Northern Hemisphere in places of natural beauty like Alaska and British Columbia. These remarkable little fish have adapted and thrive, living...
Lactose tolerance, sickle cell anemia, and bitter taste perception are three examples of recently evolved human traits.