In four lectures, Richard P. Lifton, MD, PhD, and Christine E. Seidman, MD, discuss their groundbreaking work in using genetic and molecular approaches to understand cardiovascular diseases.
This virtual lab will familiarize you with heritable diseases of the heart. Learn about the diagnostic tools used to examine and diagnose patients.
Image of the Week
An intricate three-dimensional network of blood vessels nourishes the heart.
The job of the human heart—in fact of all vertebrate hearts—is to pump oxygenated blood throughout the cells of the body and to return deoxygenated blood to lungs or gills for replenishment.
Dr. Christine Seidman describes a live demonstration of an echocardiogram, with a description of the parts of the heart that are visualized.
Dr. Richard Lifton, along with student volunteers, uses an aquarium and salt to illustrate the amount of work the kidney performs each day to maintain proper levels of ions in the body.
The heart acts as a dual pump, sending oxygen-depleted blood to the lungs to be reinvigorated and pumping oxygen-rich blood to vital organs throughout the body.
The discovery of DNA as the basis of heredity led to an explosive growth of knowledge about the human genome and allowed the identification of genes that predispose people to different diseases.
Although heart disease typically occurs after middle age, seemingly fit and healthy young individuals can die suddenly from unrecognized heart disease.
Molecular genetic approaches have identified genes that, when mutated, cause either increased or decreased blood pressure.
DVD chapter lists from the 1998 Holiday Lectures on Science, Of Hearts and Hypertension: Blazing Genetic Trails.
A guide written for teachers to accompany the 1998 Holiday Lectures on Science.
A 3-D animation that shows how plaques form in a blood vessel, leading to blockage and a heart attack.
The zebrafish heart is similar to the human heart in many respects. But unlike the human heart, the fish heart closes wounds rapidly and then regenerates to nearly full function. Fibroblast growth factor (FGF) is an important molecule in the regeneration process.
Dr. Rosenthal uses a model of a heart and an artery to describe how blockages lead to heart attack and tissue damage.