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Click & Learn
Answer the questions in this online quiz to test your knowledge of what determines the sex of a human, a fruit fly, and a snapping turtle.
Click & Learn
Learn why verifying a person's gender may be harder than you think.
Classroom Resource
A text transcript of the 2001 Holiday Lectures on Science, The Meaning of Sex: Genes and Gender.
Classroom Resource
A chapter list to accompany the DVD.
Classroom Resource
A jigsaw format activity to explore the sex determination mechanisms of seven organisms.
Video Clips
A demonstration by Dr. Meyer showing how a balance of molecular elements trigger genetic pathways that determine the sex of a C. elegans worm.
Video Clips
A demonstration by Dr. Barbara Meyer of how a branched genetic pathway can be affected by mutations in different parts of the pathway.
Video Clips
Video microscopy of mating between a male and a hermaphrodite C. elegans roundworm.
Video Clips
Video closeup of the C. elegans sperm that moves like an amoeba.
Video Clips
What does a stack of fruits and vegetables have to do with the theoretical advantages of sexual reproduction? Find out in this demonstration with student audience members and Dr. David Page.
Video Clips
Video microscopy demonstrating how sperm from an infertile male can be injected into a female egg.
Lectures
Is it a boy or a girl? Dr. David Page looks at how we define male and female and summarizes the development of human sex characteristics.
Lectures
Dr. Barbara Meyer explains the value of studying model organisms and introduces the nematode C. elegans.
Lectures
Having too many chromosomes can lead to too much gene expression. Dr. Meyer explains how the gene that controls dosage compensation in C. elegans works.
Lectures
Dr. Page explains how successive inversions and deletions of the Y chromosome during mammalian evolution have reduced it to its present form—small and sparsely populated with genes.
Animation
Meiosis, the form of cell division unique to egg and sperm production, sets the stage for sex determination by creating sperm that carry either an X or a Y sex chromosome. But what is it about the X or Y that determines sex?
Animation
This animation shows how MIX-1 facilitates both chromosome condensation and dosage compensation.
Animation
The Y chromosome has been likened to a hall of mirrors because its sequence contains many sections that appear to be palindromes. These palindromes provide a clue to some interesting events that may have occurred during the course of the chromosome's evolution.
Animation
How did the human Y chromosome become so small relative to its X counterpart? This animation depicts the 300-million-year odyssey of the sex chromosomes that began when the proto X and Y were an identical pair.
Series
Four talks focus on sex determination—the molecular and genetic mechanisms that determine whether an organism will be male, female or a hermaphrodite.
