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    Growth cones in action
    Video Clips
    The growth cones of two neurons sense and interact with one another.
    Sensory Transduction: Getting the Message
    Lectures
    Dr. Hudspeth will begin by discussing how simple organisms—such as bacteria—have the capacity to detect and react to a stimulus.
    The Science of Sight: Getting the Picture
    Lectures
    Dr. Nathans will discuss how the visual process involves the detection of light by photo-receptors in the retina.
    The Science of Sound: How Hearing Happens
    Lectures
    Dr. Hudspeth will explain the basis for the ear’s remarkable ability to detect sound through the hair cell, the sensory receptor found in the inner ear.
    Neural Processing: Making Sense of Sensory Information
    Lectures
    Dr. Nathans will complete the lecture series by clarifying what is known about the brain’s ability to process and integrate various elements of the visual system, such as color, motion, and depth.
    Plan of Action: How the Spinal Cord Controls Movement
    Lectures
    Understanding the neural circuits in the spinal cord that control movement.
    Genetics of Bitter Taste Perception
    Lectures
    How humans perceive bitter taste, and the evolution of taste perception.
    1997 Holiday Lectures on Science Teacher Guide
    Classroom Resource
    A guide written for teachers to accompany the 1997 Holiday Lectures on Science.
    Senses and Sensitivity: Neuronal Alliances for Sight and Sound
    Series
    In four talks, A. James Hudspeth, MD, PhD, and Jeremy H. Nathans, MD, PhD, discuss how sensory information is encoded and transmitted to the brain. They describe the detailed workings of two senses of great importance to humans—vision and hearing.
    Lightning-strike cabal acts like a Taser
    Animation
    Some cone snail toxins chemically hyperactivate neurons and immobilize prey, much like a Taser.
    Prialt blocks pain signaling in mice
    Animation
    Prialt does not block the mammalian motor synapse, but blocks the pain pathway in the spinal cord.
    The Cochlea
    Animation
    A dramatic illustration of how hearing happens in the ear.
    Behavior of mice that lack proprioception
    Video Clips
    Genetically engineered mice lacking proprioceptive sensory axons are not capable of well-coordinated walking.
    Demo: Proprioception makes raising a mug easy
    Video Clips
    The average person has no difficulty raising a coffee mug.
    Demo: Testing a student's proprioceptive reflex
    Video Clips
    A knee-jerk reflex depends on a simple circuit of proprioceptive sensory neurons and spinal motor neurons.
    Demo: Using spatial memory to clear an obstacle
    Video Clips
    Even without visual feedback, we are able to negotiate an obstacle using spatial memory.
    Demo: Touching thumb to fingers with proprioception
    Video Clips
    Proprioceptive feedback makes it easy to touch one's thumb to one's fingers without looking.
    Waterman touching thumb to fingers without feedback
    Video Clips
    In the absence of proprioception and visual feedback, it is impossible to touch thumb to fingers accurately.
    Without proprioception, raising a mug is difficult
    Video Clips
    A person with a disease that kills proprioceptive neurons has severe problems with the simplest of movements.