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Showing 1 - 20 of 20 results
Click & Learn
DNA microarrays, or gene chips, are an important new technology for genomic research. Learn how researchers use computing to analyze and interpret the huge datasets generated by microarray experiments.
Click & Learn
All living humans originated from populations of ancestors who migrated out of Africa less than 100,000 years ago. Learn how scientists have used genetic markers to trace the migration routes and origins of modern human populations.
Classroom Resource
A text transcript of the 2002 Holiday Lectures on Science, Scanning Life's Matrix: Genes, Proteins, and Small Molecules.
Interview
Katherine Sorber, a graduate student in the DeRisi lab, describes her research on malaria.
Lectures
Dr. Eric Lander takes us on a tour of this remarkable genetic century, describing the rapid advances in DNA sequencing technologies and information science.
Lectures
To understand life's processes, perturb them. How a process responds to an insult can provide clues about normal function or mimic a specific disease state.
Lectures
Dr. Lander explores human genetic variation and how it may affect individual susceptibility to certain diseases.
Lectures
Scientists now have the ability to create millions of new molecules. How do they test whether any of these molecules are useful?
Lectures
Dr. Friedman shows how leptin rewires neural circuits, and how population studies may identify obesity genes.
Lectures
New technologies like the Virochip harness DNA's properties to identify and fight new viruses.
Lectures
The SARS epidemic was successfully halted by a global research effort to identify a new virus.
Lectures
Genetic evidence shows that humans evolved in Africa and continue to evolve.
Lectures
A wide-ranging 45-minute discussion between Dr. Eric Lander, Dr. Stuart Schreiber, and four Washington DC-area high school teachers.
Series
In four presentations, Stuart L. Schreiber, PhD, and Eric S. Lander, PhD, open a window onto the fast-paced world of genomic science and chemical genetics.
Animation
The public Human Genome Project started by identifying unique marker sequences distributed throughout the genome. Then, many copies of a small section of DNA were randomly cleaved into smaller fragments, and each small fragment was sequenced. Because there were originally many copies of the DNA in...
Animation
In shotgun sequencing many copies of the entire genome are "blown up" into millions of small fragments. Each small fragment is sequenced. Powerful computers then assemble the individual fragments into the original configuration. Repeat sequences pose a problem for this approach because their sizes...
Animation
Gene chips, also called DNA microarrays, have a broad range of applications in current research, including enabling researchers to measure the activity of thousands of genes simultaneously. Dr. Eric Lander describes the process used to manufacture gene chips.
Animation
After a chemical biologist has made many novel small molecules by diversity-oriented synthesis, the next step is to find those that are useful. Molecules need to be "screened." Conceptually, screening is like using proteins as a custom filter to catch potentially useful small molecules.
Video Clips
Peter Skewes-Cox, and Dr. Graham Ruby, both in the DeRisi lab, explain state-of-the-art DNA sequencing and bioinformatic technologies.




