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Showing 1 - 15 of 15 results
Video Clips
Dr. Vogelstein shows video taken during a colonoscopy and the removal of a polyp.
Article
Cancer occurs when a single cell acquires the ability to reproduce aggressively and to invade other tissues. Left unchecked, this anarchy destroys the cellular society. It interferes with the body's normal function, destroys organs, and eventually kills the organism.
Classroom Resource
A text transcript of the 2003 Holiday Lectures on Science, Learning From Patients: The Science of Medicine.
Classroom Resource
A chapter list to accompany the DVD.
Lectures
Although there are numerous kinds of cancer, all stem from alterations that allow cell division to outstrip cell demise.
Lectures
The identification of hundreds of genes involved in the formation and spread of cancer is leading to promising new methods for diagnosis, prevention, and treatment.
Series
As part of the 2003 Holiday Lectures on Science, Dr. Bert Vogelstein and Dr. Huda Y. Zoghbi discuss how their patients have led to a deeper understanding of the genetic and molecular bases of neurological disorders and cancer. Thanks to these patients, researchers can now apply the knowledge...
Animation
Chronic myeloid leukemia (CML) is caused by a mutation that leads to an abnormal protein that is always active. The drug Gleevec has a shape that fits into the active site of the abnormal protein and stops its harmful effects.
Animation
A cancer tumor forms in a bed of healthy cells. The animation goes on to show how the tumor recruits blood vessels and how metastasis occurs.
Animation
Gleevec is a drug designed to interfere with the stimulation of growth in leukemia cells. This 3D animation shows how this is achieved.
Animation
A 3D animation showing the molecule p53 binds to DNA and initiates the transcription of mRNA.
Animation
This animation demonstrates how cancerous cells could be destroyed using a modified virus.
Animation
This animation shows how a growing tumor can recruit nearby blood vessels in order to gain a supply of blood.
Click & Learn
Learn about what p53 does, and how interfering with its function can lead to cancer.
