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Showing 1 - 25 of 35 results
Video Clips
Dr. Vogelstein shows video taken during a colonoscopy and the removal of a polyp.
Interview
An interview with Harith Rajagopalan, a scientist in Dr. Vogelstein's lab.
Click & Learn
Learn about the structure and function of this fascinating cellular machine.
Article
Cancer occurs when a single cell acquires the ability to reproduce aggressively and to invade other tissues. Left unchecked, this anarchy destroys the cellular society. It interferes with the body's normal function, destroys organs, and eventually kills the organism.
Classroom Resource
To accompany the lecture series Learning from Patients: The Science of Medicine.
Classroom Resource
A text transcript of the 2003 Holiday Lectures on Science, Learning From Patients: The Science of Medicine.
Classroom Resource
A chapter list to accompany the DVD.
Video Clips
Dr. Zoghbi introduces the topic of Rett syndrome by showing how development usually progresses in a young girl. She then shows an excerpt from Silent Angels, introduced by Julia Roberts, which shows how Rett syndrome affects development.
Interview
An interview with Jennifer Gatchel, a scientist in Dr. Zoghbi's lab.
Video Clips
Dr. Zoghbi shows how a mouse that has been given the gene responsible for Rett syndrome exhibits some of the same neurological symptoms as human Rett patients.
Video Clips
Dr. Zoghbi demonstrates how mice that have been given the gene responsible for spinocerebellar ataxia 1 (SCA1) are tested on a device called a rotarod to quantify the amount of ataxia present.
Video Clips
Dr. Huda Zoghbi interviews Milan Cloud, a patient who has inherited the neurological disorder spinocerebellar ataxia 1, or SCA1.
Video Clips
What do humans, flies, and worms have in common? More than you might think. See how transgenic organisms are engineered, and how they enable researchers to study genetic diseases.
Lectures
Although there are numerous kinds of cancer, all stem from alterations that allow cell division to outstrip cell demise.
Lectures
The identification of hundreds of genes involved in the formation and spread of cancer is leading to promising new methods for diagnosis, prevention, and treatment.
Lectures
Mutations in key genes can lay waste to the nervous system. By studying large families predisposed to developing these genetic disorders, scientists can identify the responsible altered gene.
Lectures
Girls with Rett syndrome develop normally for about 18 months and then begin to regress. With the help of affected girls and their families, Dr. Zoghbi and her collaborators searched for the gene responsible for this neurological disorder.
Lectures
Genetic research benefits health, but also raises thorny ethical issues.
Series
As part of the 2003 Holiday Lectures on Science, Dr. Bert Vogelstein and Dr. Huda Y. Zoghbi discuss how their patients have led to a deeper understanding of the genetic and molecular bases of neurological disorders and cancer. Thanks to these patients, researchers can now apply the knowledge...
Animation
A cancer tumor forms in a bed of healthy cells. The animation goes on to show how the tumor recruits blood vessels and how metastasis occurs.
Animation
Gleevec is a drug designed to interfere with the stimulation of growth in leukemia cells. This 3D animation shows how this is achieved.
Animation
This animation illustrates how mistakes made during DNA replication are repaired.
