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Classroom Resource
The poster from the 2010 Holiday Lectures, Viral Outbreak: The Science of Emerging Disease, illustrating the size, geometry, and different classifications of viruses.
Click & Learn
Learn about the nature of vector-borne diseases, and the life cycle of the dengue vector mosquito.
Click & Learn
Answer interactive questions to explore the logic of the Virochip microarray design, particularly how evolutionary relationships can be used to detect new viruses.
Classroom Resource
A text transcript of the 2011 Holiday Lectures on Science, Viral Outbreak: The Science of Emerging Disease.
Classroom Resource
A chapter list to accompany the DVD.
Video Clips
“The Assemblers” (Peter Skewes-Cox and Dr. Graham Ruby) sing about DNA and proteins.
Interview
Katherine Sorber, a graduate student in the DeRisi lab, describes her research on malaria.
Interview
Kate Williams, a graduate student in the Harris lab, describes her epidemiological research linking antibodies and severe dengue in Nicaragua.
Interview
Nathan Yozwiak, a graduate student in the Harris/DeRisi labs, discusses working in Nicaragua to discover a new virus infecting children.
Interview
Ben Vincent describes his summer work collecting mosquitoes for Dr. Marm Kilpatrick's research on the ecology and epidemiology of the West Nile virus.
Lectures
Learn about research aimed at thwarting denuge fever in the lab and in communities.
Lectures
New technologies like the Virochip harness DNA's properties to identify and fight new viruses.
Lectures
Understanding the immune response is essential to developing safe vaccines for dengue and other diseases.
Lectures
The SARS epidemic was successfully halted by a global research effort to identify a new virus.
Lectures
This discussion from the 2010 Holiday Lectures on Science explores the ethics of genetically-modified organisms and other topics.
Series
Watch two leading virus reasearchers explain how they use both simple and sophisticated technologies to detect and fight infectious agents.
Animation
Infection begins when the dengue virus uses receptors on an immune cell's surface to gain entry and release its genome.
Animation
Dengue virus has sophisticated mechanisms for entering a cell, for replicating its RNA genome, and for transcribing proteins.
Animation
Since the 1960s dengue fever has spread to many countries and total case numbers have exploded.
Animation
The dengue virus's outer envelope proteins form symmetrical units and overlay the lipid envelope, capsid, and the RNA genome.
Animation
DNA's chemical properties can be harnessed for a variety of biotechnology applications.
Animation
PCR is a standard laboratory technique that allows amplification of specific segments of DNA based on complementarity.
Animation
The geometric structures of viruses are beautiful and can be used, along with genomic information, to identify them.




