A quarry site in Nevada carries the evolutionary history of a population of stickleback fish that resided there when it was a freshwater lake.
This animation shows a rotating 3-D image of a stickleback skeleton. The pelvic region, including the pelvic spines, is highlighted in red. Armored plating covers the flanks of the fish. The three prominent dorsal spines give the fish its name.
As a human embryo develops, its cells become progressively restricted in the types of specialized cells that they can produce. Inner cell mass (ICM) cells of the blastocyst can make any type of body cell. Gastrula-stage cells can give rise to the cells of a given germ layer. Later, cells become...
Dr. Christine Seidman describes a live demonstration of an echocardiogram, with a description of the parts of the heart that are visualized.
An interview with Dr. Kingsley.
An interview with Stephanie Nuñez, a student in Dr. Kingsley's lab.
The hominid fossil record of the past six million years gives us surprising insights into the path of human evolution.
Comparing the artificial selection of dogs and corn with the natural selection of the stickleback fish.
The genetic mechanisms by which evolution occurs, and an overview of the evidence for evolutionary theory.
How and why butterflies and fruit flies got their spots, and the fossil record for human evolution.
In four lectures, Richard P. Lifton, MD, PhD, and Christine E. Seidman, MD, discuss their groundbreaking work in using genetic and molecular approaches to understand cardiovascular diseases.
The heart acts as a dual pump, sending oxygen-depleted blood to the lungs to be reinvigorated and pumping oxygen-rich blood to vital organs throughout the body.
Although heart disease typically occurs after middle age, seemingly fit and healthy young individuals can die suddenly from unrecognized heart disease.
Molecular genetic approaches have identified genes that, when mutated, cause either increased or decreased blood pressure.
Comparing features of a 4.4-million-year-old fossil skeleton to those of human and chimpanzee skeletons sheds light on our evolutionary history.
Learn why verifying a person's gender may be harder than you think.
A hands-on activity in which students interpret molecular diagrams and build physical models of eukaryotic gene regulation.
A hands-on activity in which students analyze the results of genetic crosses between stickleback fish with different traits.
An intricate three-dimensional network of blood vessels nourishes the heart.
Many animals have a third eyelid called a nictitating membrane that protects the eye.
The eye of a chimpanzee views the world in living color.
This interactive explores different anatomical features of the human body and what they reveal about the evolutionary history we share with other organisms, including earlier, long-extinct species.
The fins of the scalyhead sculpin are related to our arms.
Tiktaalik roseae, also known as the “fishapod,” is an animal that lived about 375 million years ago, with features of fish and four-legged animals.
The Cape Cliff lizard sports a bony body armor.
The following classroom-ready resources complement Great Transitions: The Origin of Tetrapods, which tells the story of the discovery of Tiktaalik, a creature with features common to fish and four-legged animals, or tetrapods.
The shape of our hands comes from tree-dwelling ancestors.
Dante is a healthy 10-year-old boy who has had half his cerebral cortex surgically removed to treat his seizures.
Dante is a 10-year-old boy born with hemimegalencephaly—an enlargement of half his brain.
The bill of the buff-tailed sicklebill hummingbird is perfectly shaped to collect nectar from deep within the Centropogon flower.
The poster from the 2006 Holiday Lectures on Science, Potent Biology: Stem Cells, Cloning, and Regeneration, illustrates the role of stem cells during human embryonic development.
Two views of a late pupa of an unidentified midge species (family Chironomidae).
The skull of Zinjanthropus is one of the first early hominid fossils found in Africa and provides essential clues in the story of human evolution.
App version of the popular virtual lab, introducing you to the science and techniques used to analyze the threespine stickleback fish.
A reconstruction of Anchiornis huxleyi, a feathered dinosaur that is part of the ancestral lineage of birds.
Compare and contrast the anatomy of the heart and the circulatory systems of major vertebrate groups and gain insights into their evolution.
The Lizard Evolution Virtual Lab app lets you explore the evolution of the anole lizards in the Caribbean on your iOS device.
The following classroom-ready resources complement Great Transitions: The Origin of Humans, which reveals the history of our evolutionary origins.
The muscles of the mouse’s heart contract about 600 times per minute, or a billion times in its three-year lifespan.
This activity supports the film The Origin of Species: Lizards in an Evolutionary Tree. Students are guided to sort the lizard species by appearance, then generate a phylogenetic tree using the lizards’ DNA sequences to evaluate whether species that appear similar are closely related to...
Which traits distinguish humans from other primates? When and where did these traits evolve? Analysis of the major fossil finds from Africa, dating back to 4.4 million years ago, provides answers to these questions and reveal the history of our evolutionary origins.
A close-up view of the sound-producing structure on the wing of a field cricket (Gryllus pennsylvanicus).
One of the most exciting discoveries in the long history of fossil exploration is Tiktaalik, a creature with a mix of features common to fish and four-legged animals, or tetrapods.
In the second film of the Great Transitions trilogy, paleontologist Julia Clarke takes us on a journey to uncover the evidence that birds descended from dinosaurs.
An intricate system of tubes in the kidney filters out waste products from the blood.