Howard Hughes Medical Institute 2010 Annual Report

Medical Advisory Boards

J. Michael Bishop, M.D.
Director and University Professor
G.W. Hooper Foundation
University of California, San Francisco
(Effective October 1, 2009)
Michael R. Botchan, Ph.D.
Richard and Rhoda Goldman Distinguished Professor of Biochemistry
Co-Chair of the Department of Molecular and Cell Biology
University of California, Berkeley
Gerald R. Fink, Ph.D.
Member, Whitehead Institute for Biomedical Research
Herman and Margaret Sokol Professor
American Cancer Society Professor of Genetics
Massachusetts Institute of Technology
J. Larry Jameson, M.D., Ph.D.
Vice President for Medical Affairs and Lewis Landsberg Dean
Northwestern University, Feinberg School of Medicine
(Through December 31, 2009)
Rowena G. Mathews, Ph.D.
G. Robert Greenberg Professor Emeritus of Biological Chemistry and Research
Professor Emeritus
Life Sciences Institute
University of Michigan
Janet Rossant, Ph.D.
Chief of Research
The Hospital for Sick Children, Toronto
(Effective October 1, 2009)
Carla J. Shatz, Ph.D.
Director, Bio-X
Professor of Biology and Neurobiology
James H. Clark Center
Stanford University
Bruce Stillman, Ph.D., F.R.S.
President and CEO
Cold Spring Harbor Laboratory
Craig B. Thompson, M.D.
Chairman
Professor and Scientific Director
Abramson Cancer Center
University of Pennsylvania

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Scientific Review Board

Wolfhard Almers, Ph.D.
Senior Scientist, Vollum Institute
Oregon Health and Science University
Spyros Artavanis-Tsakonas, Ph.D.
Professor of Cell Biology
Harvard Medical School
Michael Ashburner, F.R.S.
Professor of Biology
Department of Genetics
University of Cambridge
(Through December 31, 2009)
Mary Beckerle, Ph.D.
Ralph E. and Willa T. Main Presidential Professor
Executive Director, Huntsman Cancer Institute
University of Utah
Stephen J. Benkovic, Ph.D.
Evan Pugh Professor and Eberly Chair in Chemistry
The Pennsylvania State University
William A. Catterall, Ph.D.
Professor and Chair
Department of Pharmacology
University of Washington School of Medicine
Sara A. Courtneidge, Ph.D.
Professor and Director
Tumor Microenvironment Program
Director of Academic Affairs
Burnham Institute for Medical Research
Jorge E. Galán, Ph.D.
Lucille P. Markey Professor of Microbiology
Chairman
Section of Microbial Pathogenesis
Yale School of Medicine
(Through December 31, 2009)
Richard H. Goodman, M.D., Ph.D.
Director, Vollum Institute
Oregon Health and Science University
Alan Hall, Ph.D.
Chairman
Cell Biology Program
Memorial Sloan-Kettering Cancer Center
Margaret K. Hostetter, M.D.
Jean McLean Wallace Professor and Chair
Department of Pediatrics
Professor of Microbial Pathogenesis
Yale School of Medicine
Richard D. Kolodner, Ph.D.
Member
Ludwig Institute for Cancer Research, San Diego Branch
Professor of Medicine
University of California, San Diego, School of Medicine
Executive Director for Laboratory Science and Technology
Ludwig Institute for Cancer Research, New York
Robb Krumlauf, Ph.D.
Scientific Director
Stowers Institute for Medical Research
Lynn Landmesser, Ph.D.
Garvin Professor and Chair
Department of Neurosciences
Case Western Reserve University School of Medicine
Michael A. Marletta, Ph.D.
Aldo DeBenedictis Distinguished Professor of Chemistry
Professor of Biochemistry and Molecular Biology
University of California, Berkeley
Gail R. Martin, Ph.D.
Professor and Vice-Chair
Department of Anatomy
University of California, San Francisco
Diane Mathis, Ph.D.
Professor of Pathology
Harvard Medical School
W. James Nelson, Ph.D.
Rudy J. and Daphne Donohue Munzer Professor
Department of Biology and of Molecular and Cellular Physiology
James H. Clark Center
Bio-X
Stanford University
Eric N. Olson, Ph.D.
Professor and Chairman
Department of Molecular Biology
University of Texas Southwestern Medical Center at Dallas
Luis F. Parada, Ph.D.
Professor and Chairman
Department of Developmental Biology
University of Texas Southwestern Medical Center at Dallas
Gregory A. Petsko, D.Phil.
Gyula and Katica Tauber Professor of Biochemistry and Chemistry and Chair
Department of Biochemistry
Brandeis University
Adjunct Professor
Department of Neurology and Center for Neurologic Diseases
Harvard Medical School and Brigham and Women’s Hospital
Hidde Ploegh, Ph.D.
Member
Whitehead Institute for Biomedical Research
Professor of Biology
Massachusetts Institute of Technology
Janet Rossant, Ph.D.
Chief of Research
The Hospital for Sick Children, Toronto
(Through September 30, 2009)
Joshua R. Sanes, Ph.D.
Professor of Molecular and Cellular Biology
Paul J. Finnegan Family Director, Center for Brain Science
Harvard University
Robert T. Sauer, Ph.D.
Salvador E. Luria Professor
Department of Biology
Massachusetts Institute of Technology
Mark Schlissel, Ph.D.
Dean of Biological Sciences and Professor of Immunology and Pathogenesis
Department of Molecular and Cell Biology
University of California, Berkeley
David W. Tank, Ph.D.
Henry L. Hillman Professor
Department of Molecular Biology
Co-Director, Princeton Neuroscience Institute
Princeton University
David C. Van Essen, Ph.D.
Edison Professor and Head
Department of Anatomy and Neurobiology
Washington University in St. Louis School of Medicine
Christopher T. Walsh, Ph.D.
Hamilton Kuhn Professor
Department of Biological Chemistry and Molecular Pharmacology
Harvard Medical School
Huntington F. Willard, Ph.D.
Director, Institute for Genome Sciences and Policy
Nanaline H. Duke Professor of Genome Sciences
Duke University

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Science Education Advisory Board

Bruce M. Alberts, Ph.D.
Professor Emeritus
Department of Biochemistry and Biophysics
University of California, San Francisco
Bonnie L. Bassler, Ph.D.
HHMI Investigator
Squibb Professor and Director of Graduate Studies
Department of Molecular Biology
Princeton University
Sean B. Carroll, Ph.D.
HHMI Investigator
Professor of Molecular Biology, Genetics, and Medical Genetics
University of Wisconsin–Madison
Carol T. Christ, Ph.D.
President
Smith College
Carol A. Gross, Ph.D.
Professor
Department of Microbiology and Immunology
Department of Cell and Tissue Biology
University of California, San Francisco
David W. Oxtoby, Ph.D.
President
Pomona College
Shirley M. Tilghman, Ph.D.
President
Princeton University
Ronald D. Vale, Ph.D.
HHMI Investigator
William K. Hamilton Distinguished Professor
Department of Anesthesia
University of California, San Francisco
William B. Wood, Ph.D.
Emeritus Professor of Molecular, Cellular and Developmental Biology
University of Colorado at Boulder

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Janelia Farm Research Campus Advisory Committee

Jennifer Tour Chayes, Ph.D.
Managing Director
Microsoft Research New England
Joseph L. Goldstein, M.D.
Regental Professor and Chairman
Department of Molecular Genetics
University of Texas Southwestern Medical Center at Dallas
Gerald M. Rubin, Ph.D.
Chair
Vice President and Director
Janelia Farm Research Campus
Howard Hughes Medical Institute
Carla J. Shatz, Ph.D.
Director, Bio-X
Professor of Biology and Neurobiology
James H. Clark Center
Stanford University
David W. Tank, Ph.D.
Henry L. Hillman Professor
Department of Molecular Biology
Co-Director, Princeton Neuroscience Institute Princeton University
K. Vijay Raghavan, Ph.D.
Director
National Centre of Biological Sciences
Tata Institute of Fundamental Research

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Bioethics Advisory Board

Patricia A. King, J.D.
Carmack Waterhouse Professor of Law, Medicine, Ethics, and Public Policy
Georgetown Law School
Georgetown University
Harriet S. Rabb, J.D.
Vice President and General Counsel
The Rockefeller University
Harold T. Shapiro, Ph.D.
President Emeritus and Professor of Economics and Public Affairs
Princeton University

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Honors & Awards

Honors & Awards

Join us in congratulating HHMI scientists, scholars, and educators who received special recognition this year.

Annual Reflections

Annual Reflections

HHMI President Robert Tjian’s annual letter, accompanied by reflections from Trustee Hanna H. Gray.

Research Highlights

Research Highlights

Explore the work of HHMI scientists through an interactive feature that highlights some of the year’s notable discoveries.