HHMI - Howard Hughes Medical Institue

Merging lattice light sheet microscopy with adaptive optics reveals the most detailed picture yet of subcellular dynamics in multicellular organisms.

The crystal structure of a G protein commonly mutated in pituitary tumors could help researchers develop anti-cancer drugs.

Scientists have engineered ferrets genetically to study abnormally small brain size in humans – and, in the process, discovered hints as to how our brains evolved.

HHMI scientists have deconstructed the brain circuits that control parenting behavior in mice and identified discrete sets of cells that control actions, motivations, and hormonal changes involved in nurturing young animals.

A drug that reverses the effects of a cellular stress response restores learning and memory in mice with concussions. Now researchers can see the atomic-scale details of how the drug interacts with its protein target.

HHMI researchers have built mosquitobrains.org, the first map of the female mosquito brain. The new resource may ultimately uncover the circuitry behind biting and other behaviors.

A new technique may one day allow fast, simple detection of the bacterium that causes TB, as well as a way to monitor whether drugs are working.

The AP and HHMI’s Department of Science Education will expand collaboration to support health and science reporting.

Scientists have dramatically expanded the number of ancient DNA samples studied­­ – revealing vast and surprising migrations and genetic mixing of populations in our prehistoric past.